|
Symbol Name ID |
Lhcgr
luteinizing hormone/choriogonadotropin receptor MGI:96783 |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating gonadotropin level |
Decreased serum testosterone concentration |
Absence of secondary sex characteristics |
Precocious puberty |
Precocious puberty in males |
Female hypogonadism |
Hypergonadotropic hypogonadism |
Male hypogonadism |
Primary gonadal insufficiency |
| Disease(s) Associated with LHCGR | |||||||||
| familial male-limited precocious puberty | |||||||||
| Leydig cell hypoplasia |
| Mouse Phenotypes | increased adrenal gland weight |
enlarged adrenal glands |
small thymus |
bulbourethral gland hypoplasia |
abnormal prostate gland morphology |
small prostate gland anterior lobe |
increased prostate gland weight |
enlarged prostate gland |
small prostate gland |
prostate gland hypoplasia |
decreased seminal vesicle weight |
increased seminal vesicle weight |
enlarged seminal vesicle |
small seminal vesicle |
seminal vesicle hypoplasia |
absent endometrial glands |
decreased endometrial gland number |
abnormal ovary morphology |
absent corpus luteum |
absent mature ovarian follicles |
impaired ovarian folliculogenesis |
decreased ovary weight |
small ovary |
abnormal seminiferous tubule morphology |
small seminiferous tubules |
abnormal adult Leydig cell differentiation |
decreased Leydig cell number |
absent Leydig cells |
increased Leydig cell number |
decreased testis weight |
small testis |
testis hypoplasia |
cryptorchism |
prostate gland inflammation |
decreased ovary secretion |
decreased testes secretion |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||
| Lhcgrtm1(KOMP)Vlcg/Lhcgrtm1(KOMP)Vlcg | |||||||||||||||||||||||||||||||||||||
| Lhcgrtm1Hht/Lhcgrtm1Hht | |||||||||||||||||||||||||||||||||||||
| Lhcgrtm1Zmlei/Lhcgrtm1Zmlei | |||||||||||||||||||||||||||||||||||||
| Lhcgrtm1.1Pnara/Lhcgr+ | |||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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